The Universidad de Sta. Isabel (USI) is a private Catholic Vincentian university owned and run by the Daughters of Charity in Naga, Camarines Sur, Philippines. It was established by six Daughters of Charity sisters who arrived in the Bicol region (Philippines) on April 4, 1868 with Bishop of Caceres, Most Rev. Francisco Gainza, O.P., founder of Colegio de Sta. Isabel. A Royal Decree of Queen Isabella II of Spain dated 5 November 1867 granted to the Lord Don Fray Francisco Gainza, Bishop of Nueva Caceres, the creation of a school for girls (escuela de niñas) which will be under the care of the Hijas de Caridad.
The school was opened on April 12, 1868. In Sept. 18, 1875, Colegio de Sta. Isabel became the first normal school for women in the Philippines and Southeast Asia under the name Escuela Normal de Maestras of Colegio de Sta. Isabel.Colegio de Sta. Isabel achieved its university status in August 2001, and was renamed Universidad de Sta. Isabel.
The main campus of the Universidad de Sta. Isabel is campus is located at Elias Angeles St., Bagumbayan Sur, Naga City. An annex campus is located at Panganiban Drive, Naga City and a satellite campus in Pili, Camarines Sur.
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